{"id":1532,"date":"2023-09-06T00:00:00","date_gmt":"2023-09-06T00:00:00","guid":{"rendered":"https:\/\/nurs.essaybishops.com\/?p=1532"},"modified":"2025-09-30T18:16:42","modified_gmt":"2025-09-30T18:16:42","slug":"sabrina-is-a-26-year-old-female","status":"publish","type":"post","link":"https:\/\/www.homeworkacetutors.com\/nursing\/sabrina-is-a-26-year-old-female\/","title":{"rendered":"Sabrina is a 26 year old female &#8211; NURS 652"},"content":{"rendered":"<p class=\"ds-markdown-paragraph\"><strong>Course:<\/strong>\u00a0NURS 652: Advanced Pharmacology for Nurse Practitioners<br \/>\n<strong>Assignment Title:<\/strong>\u00a0Pharmacotherapeutic Management in Autoimmune Neurological Disorders<br \/>\n<strong>Due Date:<\/strong>\u00a0[Insert Date, 2025]<br \/>\n<strong>Points:<\/strong>\u00a0100<\/p>\n<p class=\"ds-markdown-paragraph\"><strong>Scenario:<\/strong><\/p>\n<p class=\"ds-markdown-paragraph\"><strong>Elijah<\/strong>\u00a0is a 34-year-old male recently diagnosed with Myasthenia Gravis (MG). He is an elementary school teacher and has noticed increasing difficulty with speech projection and fatigue towards the end of the school day. During a follow-up telehealth appointment with the neurology clinic&#8217;s Nurse Practitioner, he expresses anxiety about how the disease will affect his ability to work and his daily life. He is particularly concerned about the weakness in his facial and oropharyngeal muscles, as well as the generalized fatigue. The NP explains that while MG is an autoimmune disorder targeting the neuromuscular junction, its symptoms can fluctuate and significantly impact his functional status, respiratory function, and quality of life.<\/p>\n<p class=\"ds-markdown-paragraph\">As the advanced practice nurse, you must develop a comprehensive pharmacotherapeutic plan to manage Elijah&#8217;s symptoms, improve his muscle strength, and prevent disease-related complications.<\/p>\n<p class=\"ds-markdown-paragraph\"><strong>Assignment Instructions:<\/strong><\/p>\n<p class=\"ds-markdown-paragraph\">Write a 3- to 4-page scholarly paper (excluding title page and references) that addresses the following prompts. Your paper must be in APA 7th Edition format and integrate evidence from at least\u00a0<strong>four<\/strong>\u00a0peer-reviewed sources published within the last five years (2020-2025).<\/p>\n<ol start=\"1\">\n<li>\n<p class=\"ds-markdown-paragraph\"><strong>Case Summary and Clinical Decisions:<\/strong>\u00a0Briefly summarize the patient case study, including the specific symptoms and concerns presented by Elijah. Based on the case, outline and justify\u00a0<strong>three distinct pharmacotherapeutic decisions<\/strong>\u00a0you would implement for his initial management.<\/p>\n<\/li>\n<li>\n<p class=\"ds-markdown-paragraph\"><strong>Evidence-Based Justification:<\/strong>\u00a0For each of the three pharmacotherapeutic decisions, explain how they are supported by current evidence-based literature. Be specific and provide examples from recent, high-quality studies or clinical practice guidelines. Justify your drug choices, dosing considerations (e.g., timing related to his work schedule), and monitoring parameters.<\/p>\n<\/li>\n<li>\n<p class=\"ds-markdown-paragraph\"><strong>Goals of Therapy:<\/strong>\u00a0What were you hoping to achieve with each of the recommended pharmacotherapeutic decisions? Link each goal to a specific patient concern or symptom from the case (e.g., improve vocal strength for teaching, reduce afternoon fatigue, prevent myasthenic crisis). Support your intended outcomes with evidence from the literature.<\/p>\n<\/li>\n<li>\n<p class=\"ds-markdown-paragraph\"><strong>Anticipating and Managing Differences in Outcomes:<\/strong>\u00a0In MG, patient response to initial therapy can be variable. For at least one of your recommended decisions, explain a potential scenario where the outcome might differ from what you expected to achieve (e.g., inadequate symptom control, side effects). Describe a specific, evidence-based alternative or adjunct therapy you would consider in that situation.<\/p>\n<\/li>\n<\/ol>\n<h3>References<\/h3>\n<p class=\"ds-markdown-paragraph\"><strong>Farmakidis, C., Pasnoor, M., Dimachkie, M. M., &amp; Barohn, R. J. (2021).<\/strong>\u00a0Treatment of Myasthenia Gravis.\u00a0<em>Neurologic Clinics, 39<\/em>(1), 133\u2013148.<\/p>\n<p class=\"ds-markdown-paragraph\"><strong>Narayanaswami, P., Sanders, D. B., Wolfe, G., Benatar, M., Cea, G., Evoli, A., &#8230; &amp; Guidelines Development, Dissemination, and Implementation Subcommittee of the American Academy of Neurology. (2020).<\/strong>\u00a0International Consensus Guidance for Management of Myasthenia Gravis: 2020 Update.\u00a0<em>Neurology, 94<\/em>(7), 299\u2013313.<\/p>\n<p class=\"ds-markdown-paragraph\"><strong>Muppidi, S., &amp; Wolfe, G. I. (2022).<\/strong>\u00a0New Therapies in Myasthenia Gravis.\u00a0<em>Frontiers in Neurology, 13<\/em>, 821040.<\/p>\n<p><strong>Andersen, J. B., Engeland, A., &amp; Owe, J. F. (2023).<\/strong>\u00a0Fatigue in myasthenia gravis: a systematic review.\u00a0<em>Acta Neurologica Scandinavica, 2023<\/em>(1), 1-12.<\/p>\n<p>______________________________________________________________________________________________________________<\/p>\n<p>Sabrina is a 26 year old female who has just been diagnosed with multiple sclerosis. She has scheduled an appointment for a follow up with her physician but has several questions about her diagnosis and is calling the Nurse Helpline for her hospital network. As she talks with the advanced practice nurse, she learns that her diagnosis also impacts her neurologic and musculoskeletal systems. Although multiple sclerosis is an autoimmune disorder, both the neurologic and musculoskeletal systems will be affected by adverse symptoms that Sabrina needs to be aware of and for which specific drug therapy plans and other treatment options need to be decided on.<br \/>\nAs an advanced practice nurse, what types of drugs will best address potential neurologic and musculoskeletal symptoms Sabrina might experience?<\/p>\n<p>Write a 1- to 2-page summary paper that addresses the following:<br \/>\n\u2022 Briefly summarize the patient case study you were assigned, including each of the three decisions you took for the patient presented.<br \/>\n\u2022 Based on the decisions you recommended for the patient case study, explain whether you believe the decisions provided were supported by the evidence-based literature. Be specific and provide examples. Be sure to support your response with evidence and references from outside resources.<br \/>\n\u2022 What were you hoping to achieve with the decisions you recommended for the patient case study you were assigned? Support your response with evidence and references from outside resources.<br \/>\n\u2022 Explain any difference between what you expected to achieve with each of the decisions and the results of the decision in the exercise. Describe whether they were different. Be specific and provide examples.<\/p>\n<p>Apa format at least 3 referneces<\/p>\n<p>Introduction<\/p>\n<p>Multiple sclerosis (MS) is an autoimmune disorder that affects the central nervous system (CNS) by damaging the myelin sheath surrounding the neurons. The disease is characterized by a wide range of neurological and musculoskeletal symptoms, which can significantly impact the patient&#8217;s quality of life. In this case study, Sabrina, a 26-year-old female, has been diagnosed with MS and is seeking advice on the potential symptoms and drug therapies that can help manage them.<\/p>\n<p>Patient Case Study<\/p>\n<p>Sabrina is a 26-year-old female who has been diagnosed with MS. She has concerns about the potential neurological and musculoskeletal symptoms that may arise as a result of the disease. As an advanced practice nurse, I recommended the following decisions for Sabrina:<\/p>\n<p>Medication Therapy: I recommended that Sabrina be started on disease-modifying therapies (DMTs) to help reduce the frequency and severity of MS relapses. Some of the DMTs that have been shown to be effective in managing MS include interferon-beta, glatiramer acetate, dimethyl fumarate, and fingolimod.<\/p>\n<p>Symptomatic Treatment: I recommended that Sabrina be prescribed medications to manage her specific symptoms. For example, muscle spasms and spasticity can be managed with baclofen, tizanidine, or dantrolene. Pain can be managed with nonsteroidal anti-inflammatory drugs (NSAIDs), acetaminophen, or opioids.<\/p>\n<p>Physical Therapy: I recommended that Sabrina undergo physical therapy to help manage her musculoskeletal symptoms. Physical therapy can help improve muscle strength, flexibility, and balance, which can improve her overall mobility and reduce the risk of falls.<\/p>\n<p>Evidence-Based Literature<\/p>\n<p>The decisions that I recommended for Sabrina are supported by the evidence-based literature. Several studies have demonstrated the efficacy of DMTs in reducing MS relapses and slowing down disease progression (Lublin et al., 2014; Ontaneda &amp; Fox, 2015). Similarly, medications such as baclofen and tizanidine have been shown to be effective in managing muscle spasms and spasticity (Bhattacharyya et al., 2015; Flachenecker et al., 2014). Finally, physical therapy has been shown to improve muscle strength, balance, and overall mobility in MS patients (Kargarfard et al., 2012; Rasova et al., 2011).<\/p>\n<p>Expected Outcomes<\/p>\n<p>The decisions that I recommended for Sabrina were aimed at reducing the frequency and severity of MS relapses, managing her specific symptoms, and improving her overall mobility and quality of life. I expected that Sabrina would experience a reduction in the number and severity of her relapses, as well as a reduction in her musculoskeletal symptoms. I also expected that physical therapy would improve her overall mobility and reduce the risk of falls.<\/p>\n<p>Conclusion<\/p>\n<p>MS is a complex disease that can have a significant impact on a patient&#8217;s neurological and musculoskeletal systems. The decisions that I recommended for Sabrina, including medication therapy, symptomatic treatment, and physical therapy, are supported by the evidence-based literature and are aimed at managing her specific symptoms and improving her overall quality of life.<\/p>\n<p>References:<\/p>\n<p>Bhattacharyya, S., Darby, R. R., Raibagkar, P., &amp; Gonzales, C. (2015). Musculoskeletal complications of multiple sclerosis. Neurology Clinical Practice, 5(2), 135-142.<\/p>\n<p>Flachenecker, P., Henze, T., &amp; Zettl, U. K. (2014). Spasticity in patients with multiple sclerosis\u2014clinical characteristics, treatment and quality of life. Acta Neurologica Scandinav<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Course:\u00a0NURS 652: Advanced Pharmacology for Nurse Practitioners Assignment Title:\u00a0Pharmacotherapeutic Management in Autoimmune Neurological Disorders Due Date:\u00a0[Insert Date, 2025] Points:\u00a0100 Scenario: Elijah\u00a0is a 34-year-old male recently diagnosed with Myasthenia&hellip;<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[53,3388,3387,58,59,55,3389,56,3246,54],"tags":[2237,67,1624,344,3385,3386,1681],"class_list":["post-1532","post","type-post","status-publish","format-standard","hentry","category-masters-essays","category-advanced-pharmacology-for-nurse-practitioners","category-all-assignment-help","category-australia-dissertation-writers","category-help-write-my-assignment","category-i-need-help-writing-a-page-paper-assignment","category-neurological-disorders","category-pay-someone-to-write-a-paper-for-you","category-tropical-essays-paper-writing-service-tropicalessays-com","category-website-that-writes-assignments","tag-advanced-practice-nursing","tag-assignment-help-by-uks-no-1-writing-service","tag-evidence-based-practice","tag-global-assignment-help","tag-myasthenia-gravis-treatment","tag-neuromuscular-junction-disorders","tag-pharmacotherapy"],"_links":{"self":[{"href":"https:\/\/www.homeworkacetutors.com\/nursing\/wp-json\/wp\/v2\/posts\/1532","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.homeworkacetutors.com\/nursing\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.homeworkacetutors.com\/nursing\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.homeworkacetutors.com\/nursing\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.homeworkacetutors.com\/nursing\/wp-json\/wp\/v2\/comments?post=1532"}],"version-history":[{"count":1,"href":"https:\/\/www.homeworkacetutors.com\/nursing\/wp-json\/wp\/v2\/posts\/1532\/revisions"}],"predecessor-version":[{"id":10531,"href":"https:\/\/www.homeworkacetutors.com\/nursing\/wp-json\/wp\/v2\/posts\/1532\/revisions\/10531"}],"wp:attachment":[{"href":"https:\/\/www.homeworkacetutors.com\/nursing\/wp-json\/wp\/v2\/media?parent=1532"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.homeworkacetutors.com\/nursing\/wp-json\/wp\/v2\/categories?post=1532"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.homeworkacetutors.com\/nursing\/wp-json\/wp\/v2\/tags?post=1532"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}