\u00a9ACU 2022 1
\nBIOL121 ASSIGNMENT 3: Written assessment
\nScenario: David
\nDavid is a 41-year-old male, who has made an appointment to see his GP for his biannual health check. He
\ntells the doctor that he has been feeling \u201ca bit puffed\u201d walking around the course during his weekly game of
\ngolf and that he seems to be urinating more frequently of late. David reports he has gained nine kilos since
\nhis 30th birthday, and his waist measurement has expanded. He laughs this off as \u201cmiddle-aged spread\u201d and
\nsays his wife tells him he needs to watch what he eats and drink less alcohol. David works as a software
\nengineer, which he has been finding very stressful of late, and spends a lot of his time in the office sitting in
\nfront of a computer, snacking on his favourite salt and vinegar chips. David and his wife are keen to start a
\nfamily but have not yet been successful in conceiving.
\nOn the advice of his doctor, David has been taking aspirin in the evenings for the past 18 months to lower his
\nrisk of heart attack and Zocor\u00ae to address cholesterol.
\nPhysical examination:
\nHeight 174 cm
\nWeight 94 kg
\nAppearance Neat appearance, overweight, pale
\nTemperature 37.1\u25e6
\nC
\nBlood work Blood type = O+
\nBlood glucose = 10 mmol\/L
\nBlood Testosterone levels = 154 ng\/dL
\nGnRH = low
\nBP 155\/99 mm Hg
\nRespiratory rate 19 bpm
\nDiet Mostly healthy meals. Snacks on high
\nfat & sugar, processed foods. Heavy
\nalcohol consumption.
\nPast patient history Ex-smoker. Regular check-ups every six
\nmonths. Cholesterol levels have been
\nhigh at the last three check-ups. Takes
\nAspirin in the evenings. Gall bladder
\nremoved 5 years ago.
\nSocial status Lives with his wife and mother-in-law.
\nSexually active.
\nUrinalysis:
\nBlood –
\nBilirubin –
\nUrobilinogen 0.1 mg\/dL
\nKetone –
\nProtein –
\nNitrite –
\nGlucose ++
\npH 6
\nSpecific Gravity 1.035
\nLeukocytes –
\n\u00a9ACU 2022 2
\nAll topics and their key points listed below must be discussed in your essay
\nTopic 1: Reproduction (10 marks total)
\nDavid and his wife are keen to start a family but have had no success so far. Considering David\u2019s blood test
\nresults, indicate whether there is need for further investigation. Your discussion should include the
\nhomeostatic regulation of male reproductive physiology and the relevant glands, cells, and hormones. (10
\nmarks)
\nTopic 2: Respiratory system (5 marks total)
\nDavid is late for work and the lift is broken; he must run up six flights of stairs to make it on time.
\nDescribe the gas exchange occurring between David\u2019s blood and the skeletal muscles in his legs. Discuss how
\nthe rate of gas exchange was affected during the run up the stairs (i.e., during exercise). (5 marks)
\nTopic 3: Digestion\/metabolism (8 marks total)
\nAfter speaking to his doctor, David has decided to try to lose weight and he going to start a diet\u2026tomorrow.
\nTonight, David is enjoying his last high carbohydrate\/high fat meal for a while.
\nDiscuss the potential impact of David\u2019s gall bladder removal upon his ability to digest his dinner. (4.5 marks)
\nState the hormone that is MOST active in maintaining David\u2019s blood glucose levels at this time. Explain your
\nanswer. (3.5 marks)
\nTopic 4: Pharmacology (7 marks total)
\nUnder the advice of his doctor, David has taken Zocor\u00ae tablets each evening for the past 18 months.
\nDiscuss the route of administration, which route the drug is likely to be excreted after administration, and its
\nlikely bioavailability. Justify your response by discussing whether the drug would be subjected to hepatic first
\npass. (4 marks)
\nTo help with weight loss, a friend has advised David to drink grapefruit juice with his meals.
\nAs a health care professional, would you consider this to be a good idea for David? In your answer, discuss
\nthe role of the liver in the administration of Zocor and grapefruit juice? (3 marks)<\/p>\n","protected":false},"excerpt":{"rendered":"
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